Can you use PLR to submit a Squidoo lens? Provided you rewrite it enough, definitely. You may even be interested in just submitting that lens as a means of generating charity donations, as increasingly more people are doing. Alternatively, you may want to promote one of your products using that lens. The key is to rewrite it sufficiently for uniqueness and interest.
A good tip to creating a Squidoo lens out of PLR base content is to “skew” the PLR article towards a specific position, usually one different from the original stance it takes. The real purpose of this tactic is to personalise the article and make it more distinctive. Turning a basic wedding plr piece into an article about what wedding ideas are still stylish and what may now be considered so cliché as to be bad, for example, is one way of generating a unique and interesting lens in which people shall be interested. Rewrite the content to include your opinion on the topic.